What kind of bed do you want? Are you lazy and do you know that you are not going to change the bed configuration every day and still prefer a fixed bed? With the advantage that it gives you more storage space under the bed. Or do you want to use that space for both a bed and a large table where you can eat or work. A plus of this setup is that you can also use this space to hang out with friends. Or you go somewhere in between such as a fold-out couch/bed, which creates more open space during the day but still enjoys a larger bed to sleep in.
Besides, how big do you want your bed? Do you like to lie in your bed like a starfish or is a single bed big enough? Besides, the bigger the bed, the smaller the rest of your layout will be.